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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MATK All Species: 11.82
Human Site: Y425 Identified Species: 23.64
UniProt: P42679 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42679 NP_002369.2 507 56469 Y425 F S Y G R A P Y P K M S L K E
Chimpanzee Pan troglodytes XP_512276 328 36052 E259 K E V S E A V E K G Y R M E P
Rhesus Macaque Macaca mulatta XP_001101430 450 50702 S381 I L L W E I Y S F G R V P Y P
Dog Lupus familis XP_854815 843 91685 Y664 F S Y G R A P Y P K M S L K E
Cat Felis silvestris
Mouse Mus musculus P41242 505 56038 Y423 F S Y G R A P Y P K M S L K E
Rat Rattus norvegicus P41243 467 51878 E398 K E V S E A V E K G Y R M E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P41239 450 50733 S381 I L L W E I Y S F G R V P Y P
Frog Xenopus laevis P13116 532 59718 Y462 T T K G R V P Y P G M V N R E
Zebra Danio Brachydanio rerio XP_695792 445 50295 I376 Y G V L L W E I F S Y G R Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731611 1052 113728 W981 W S F G I L L W E I Y S F G R
Honey Bee Apis mellifera XP_393399 493 55500 F423 L L W E I Y S F G R V P Y P R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795344 763 85563 W694 W S Y G I F M W E L Y S F G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 47.1 56.8 N.A. 87.1 82.2 N.A. N.A. 46.9 34 56 N.A. 24.8 40 N.A. 32.2
Protein Similarity: 100 64.6 64.6 58.8 N.A. 92.3 87.5 N.A. N.A. 65.6 49.2 71.4 N.A. 33.1 57.5 N.A. 42.9
P-Site Identity: 100 6.6 0 100 N.A. 100 6.6 N.A. N.A. 0 46.6 0 N.A. 20 0 N.A. 26.6
P-Site Similarity: 100 20 0 100 N.A. 100 20 N.A. N.A. 0 60 13.3 N.A. 40 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 42 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 17 0 9 34 0 9 17 17 0 0 0 0 17 34 % E
% Phe: 25 0 9 0 0 9 0 9 25 0 0 0 17 0 0 % F
% Gly: 0 9 0 50 0 0 0 0 9 42 0 9 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 25 17 0 9 0 9 0 0 0 0 0 % I
% Lys: 17 0 9 0 0 0 0 0 17 25 0 0 0 25 0 % K
% Leu: 9 25 17 9 9 9 9 0 0 9 0 0 25 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 34 0 17 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 34 0 34 0 0 9 17 9 42 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 34 0 0 0 0 9 17 17 9 9 25 % R
% Ser: 0 42 0 17 0 0 9 17 0 9 0 42 0 0 0 % S
% Thr: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 25 0 0 9 17 0 0 0 9 25 0 0 0 % V
% Trp: 17 0 9 17 0 9 0 17 0 0 0 0 0 0 0 % W
% Tyr: 9 0 34 0 0 9 17 34 0 0 42 0 9 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _